Article
Genetic variations in key inflammatory cytokines exacerbates the risk of diabetic nephropathy by influencing the gene expression.
Gene - 30 Jun 2018
Hameed Iqra, Masoodi Shariq R, Malik Perveez A, Mir Shahnaz A, Ghazanfar Khalid, Ganai Bashir A
Abstract excerpt
BACKGROUND: Diabetic nephropathy is the single strongest predictor of mortality in patients with diabetes. The development of overt nephropathy involves important inter-individual variations, even after adjusting for potential confounding influences of modifiable and non-modifiable risk factors. Genome-wide transcriptome studies have reported the activation of inflammatory signaling pathways and there is mounting...
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