Impact of IL-6 rs1800795 and IL-17A rs2275913 gene polymorphisms on the COVID-19 prognosis and susceptibility in a sample of Iranian patients.

doi:10.1016/j.cyto.2023.156445

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Article

Impact of IL-6 rs1800795 and IL-17A rs2275913 gene polymorphisms on the COVID-19 prognosis and susceptibility in a sample of Iranian patients.

Cytokine - 1 Feb 2024

Khafaei Mostafa, Asghari Reza, Zafari Fariba, Sadeghi Morteza

Abstract excerpt

BACKGROUND: From asymptomatic to acute and life-threatening pulmonary infection, the clinical manifestations of COVID-19 are highly variable. Interleukin (IL)-6 and IL-17A are key drivers of hyper inflammation status in COVID-19, and their elevated levels are hallmarks of the infection progression. To explore whether prognosis and susceptibility to COVID-19 are linked to IL-6 rs1800795 and IL-17A rs2275913, these...

Topics

COVID-19
Genetic Predisposition to Disease
Interleukin-6
Interleukin-17
Iran
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Female

Adult

Middle Aged

Polymorphism, Single Nucleotide

Prognosis

Respiratory Rate

Source

Open in PubMed

Identifiers

PMID: 38056249
DOI: 10.1016/j.cyto.2023.156445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-38056249-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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