Article
Genetic and Phenotypic Characterization of in-Host Developed Azole-Resistant Aspergillus flavus Isolates
25 Feb 2021
Abstract excerpt
Aspergillus flavus is a pathogenic fungal species that can cause pulmonary aspergillosis, and triazole compounds are used for the treatment of these infections. Prolonged exposure to azoles may select for compensatory mutations in the A. flavus genome, resulting in azole resistance. Here, we characterize a series of 11 isogenic A. flavus strains isolated from a patient with pulmonary aspergillosis. Over a period...
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