Article
Association of Family History and Polygenic Risk Scores With Prostate Cancer in Africa.
JCO global oncology - 1 Mar 2026
Odole Iyanuoluwa, Andrews Caroline, Agalliu Ilir, Rohan Thomas, Fernandez Pedro W, Irusen Hayley, Ntlaba Shome J, Janivara Rohini, Lachance Joseph, Baichoo Shakuntala, Mensah James E, Adjei Andrew A, Abrahams Afua O D, Quarchie Majorie Ntiwa, Aisuodionoe-Shadrach Oseremen I, Nwegbu Maxwell M, Jamda Mustapha A, Oluwole Peter O, Chen Wenlong Carl, Joffe Maureen, Adusei Ben, Doherty Sean, Pentz Audrey, Adebiyi Akindele, Ogunbiyi Olufemi, Jalloh Mohamed, Rebbeck Timothy R
Abstract excerpt
PURPOSE: African ancestry and family history (FHx) of prostate cancer (CaP) are among the few established CaP risk factors. Few studies have evaluated the association of FHx of CaP with the risk of this disease in African men. METHODS: Using the Men of African Descent and Carcinoma of the Prostate (MADCaP) network, we evaluated the association of self-reported FHx of CaP in fathers and brothers in a case-control...
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