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Article

Participant ascertainment is differentially related to phenotypic characteristics and alcohol-related genetic liability in a sample with severe alcohol use disorder.

Alcohol, clinical & experimental research - 1 Mar 2026

Edwards Alexis C, Passero Kristin, Eglovitch Michelle, Polak Kathryn, Parlier-Ahmad Anna Beth, Ngjelina Enkelejda, Stephenson Mallory, Lannoy Severine, Svikis Dace, Kendler Kenneth

Abstract excerpt

BACKGROUND: Alcohol use disorder (AUD) is a common substance use disorder associated with a range of sociodemographic, behavioral, and genetic factors. The current study characterizes variation in such factors as a function of ascertainment strategy in a sample of individuals with a lifetime history of severe AUD. METHODS: Participants (N = 10,804) were recruited through substance use treatment facilities or...

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Identifiers

PMID: 41802851
DOI: 10.1111/acer.70276
PMCID: PMC12971253

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