Article

Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease

2020-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWASs) of the Alcohol Use Disorder Identification Test (AUDIT), a ten-item screener for alcohol use disorder (AUD), have elucidated novel loci for alcohol consumption and misuse. However, these studies also revealed that GWASs can be influenced by numerous biases (e.g., measurement error, selection bias), which have led to inconsistent genetic correlations betwee...

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Literature Corpus work: 0abb3388-dfed-552b-b1a5-3320769a1631
DOI: 10.1101/2020.09.21.304196

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