Article
Assessing measurement bias in substance use disorder criteria associated with childhood adversity and genetic liability.
Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors - 1 Aug 2026
Davis Christal N, SooHoo Jackson, Han Angela, Gelernter Joel, Feinn Richard, Kranzler Henry R
Abstract excerpt
OBJECTIVE: The diagnosis and severity of substance use disorders (SUDs) are classified by the number of criteria endorsed. However, environmental and genetic factors may influence criterion endorsement. To evaluate this, we tested for differential item functioning of SUDs criteria by adverse childhood events (ACEs) and SUD polygenic scores. METHOD: In 10,275 Yale-Penn participants (Mage = 40.59 years, 56.2% male,...
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