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Article

Genetic relationship between the addiction diagnosis in adults and their childhood measure of addiction liability.

Behavior genetics - 1 Jan 2015

Vanyukov Michael, Kim Kevin, Irons Daniel, Kirisci Levent, Neale Michael, Ridenour Ty, Hicks Brian, Tarter Ralph, Reynolds Maureen, Kirillova Galina, McGue Matt, Iacono William

Abstract excerpt

Transmissible liability index (TLI), developed employing a high-risk design and item response theory, enables quantification of the latent trait of liability to drug use disorders (DUD) in children. TLI has been shown to have high heritability and predict DUD in young adulthood. This study extends prior research and determines the genetic contribution of DUD liability measured by TLI to adult liability as indexed...

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Source

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Identifiers

PMID: 25502189
DOI: 10.1007/s10519-014-9684-4
PMCID: PMC4445715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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