Article
Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liability.
Behavior genetics - 1 May 2009
Vanyukov Michael M, Kirisci Levent, Moss Lisa, Tarter Ralph E, Reynolds Maureen D, Maher Brion S, Kirillova Galina P, Ridenour Ty, Clark Duncan B
Abstract excerpt
The inability to quantify the risk for disorders, such as substance use disorders (SUD), hinders etiology research and development of targeted intervention. Based on the concept of common transmissible liability to SUD related to illicit drugs, a method enabling quantification of this latent trait has been developed, utilizing high-risk design and item response theory. This study examined properties of a SUD...
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