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Article

Polygenic risk scores in familial hypercholesterolemia. Do they have a role?

Current opinion in lipidology - 1 Jun 2026

Paquette Martine, Guay Simon-Pierre, Baass Alexis

Abstract excerpt

PURPOSE OF REVIEW: Risk assessment in patients with familial hypercholesterolemia (FH) remains an important clinical challenge. The polygenic susceptibility for plasma lipoprotein traits or coronary artery disease (CAD) can be assessed by polygenic risk scores (PRS). The purpose of this review is to discuss the potential roles of PRS in the context of FH management. RECENT FINDINGS: Recent studies suggested that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41762748
DOI: 10.1097/MOL.0000000000001029

Genes

FH
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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