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Article

Causal effects of hypertensive disorders of pregnancy on future gynecologic tumors: A two-sample Mendelian randomization study.

Cancer medicine - 1 May 2024

Zhou Le, Liu Xinghui, He Guolin, Sun Chuntang

Abstract excerpt

BACKGROUND: Numerous observational studies have investigated the potential link between hypertensive disorders of pregnancy (HDPs) and the subsequent risks of gynecologic tumors, yet the findings have been inconsistent. In this study, we utilized Mendelian randomization (MR) approach to assess the influence of HDPs on the future risks of ovarian, cervical, endometrial, and breast cancer and uterine fibroids,...

Topics

Humans
Female
Mendelian Randomization Analysis
Pregnancy
Genome-Wide Association Study
Genital Neoplasms, Female
Hypertension, Pregnancy-Induced
Risk Factors
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38800978
DOI: 10.1002/cam4.7300
PMCID: PMC11129165

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