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Uterine leiomyoma causes an increase in systolic blood pressure: a two-sample Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Xu Hui, Ma Yuxia, Long Yi, Liu Ren, Cheng Ziyang, Xie Xiuzhen, Han Xingjun, Wang Xuan

Abstract excerpt

Objectives: Hypertension and hypertensive disorders of pregnancy (HDP) are common diseases in women at different stages, which affect women's physical and mental health, and the impact of the latter on the offspring cannot not be ignored. Observational studies have investigated the correlation between uterine leiomyoma (UL) and the above conditions, but the relationship remains unclear. In this study, we employed...

Topics

Humans
Female
Mendelian Randomization Analysis
Leiomyoma
Uterine Neoplasms
Blood Pressure
Pregnancy
Genome-Wide Association Study
Polymorphism, Single Nucleotide
Hypertension
Hypertension, Pregnancy-Induced

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38800482
DOI: 10.3389/fendo.2024.1373724
PMCID: PMC11116641

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