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Article

The functional minisatellite at the 3'-UTR of SLC6A3/DAT1 and dementia spectrum disorders: an association study in a population of Central Italy.

BMC medical genomics - 28 Feb 2026

Torbidoni-Baldassari Benedetta, Guazzarini Anna Giulia, Rezza Gabriele, Bastiani Patrizia, Cecchetti Roberta, Mecocci Patrizia, Napolioni Valerio

Abstract excerpt

BACKGROUND: Dementia comprises a spectrum of neurodegenerative disorders marked by progressive cognitive and behavioural decline, with Alzheimer’s disease (AD) being the most prevalent form. While several genetic factors have been implicated in AD pathogenesis, a significant portion of heritability remains unexplained. One potential contributor to this “missing heritability” is structural variation within...

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Identifiers

PMID: 41761178
DOI: 10.1186/s12920-026-02341-6
PMCID: PMC13064044

Genes

APOE
SLC6A3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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