Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: a 90-month longitudinal study.

doi:10.1002/ajmg.b.32220

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Article

Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: a 90-month longitudinal study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2014

Scholz Claus-Jürgen, Jungwirth Susanne, Danielczyk Walter, Weber Heike, Wichart Ildiko, Tragl Karl Heinz, Fischer Peter, Riederer Peter, Deckert Jürgen, Grünblatt Edna

Abstract excerpt

Alzheimer's disease (AD) and depression (DE) are common psychiatric disorders strongly intertwined with one another. Nevertheless, etiology and early diagnosis of the disorders are still elusive. Several genetic variations have been suggested to associate with AD and DE, particularly in genes involved in the serotonergic system such as the serotonin transporter (SERT/SLC6A4), responsible for the removal from the...

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PMID: 24443391
DOI: 10.1002/ajmg.b.32220

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