Association of dopamine transporter gene DAT1 40-bp 3' UTR VNTR polymorphism (rs28363170) with Psychiatric disorders susceptibility: A study from the Pakistani population.

doi:10.1007/s11033-026-12392-8

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Association of dopamine transporter gene DAT1 40-bp 3' UTR VNTR polymorphism (rs28363170) with Psychiatric disorders susceptibility: A study from the Pakistani population.

Molecular biology reports - 10 Aug 2026

Hashmi Aisha Nasir, Dharejo Raees Ahmed, Qamar Raheel, Omer Wafa, Azam Maleeha

Abstract excerpt

OBJECTIVE: The dopamine transporter gene (DAT1) is a critical component of the dopaminergic system and has been consistently implicated in several neuropsychiatric diseases, but the disease mechanism remains elusive. Being multifactorial with a genetic basis, the study aimed to find out the relationship between the DAT1 40 bp 3'UTR Variable Number Tandem Repeat (VNTR) (rs28363170) and major depressive disorder...

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PMID: 42573657
DOI: 10.1007/s11033-026-12392-8

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