Article
Investigation of the role of the dopamine transporter in susceptibility to behavioural and psychological symptoms of patients with probable Alzheimer's disease.
Dementia and geriatric cognitive disorders - 1 Jan 2008
Pritchard Antonia L, Pritchard Colin W, Bentham Peter, Lendon Corinne L
Abstract excerpt
BACKGROUND/AIMS: Alzheimer's disease patients commonly suffer from behavioural and psychological symptoms of dementia (BPSD); a genetic component to the development of BPSD has been demonstrated. Genetic risk factors for other psychiatric disorders have been implicated in BPSD; however, this is the first known investigation of the dopamine transporter (DAT1) gene in BPSD. METHODS: Our large cohort of 395 patients...
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