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Article

Epigenomic differences between osteoarthritis grades in primary cartilage

23 Jul 2024

Abstract excerpt

OBJECTIVE: Osteoarthritis is a common and complex joint disorder that shows higher prevalence and greater disease severity in women. Here, we investigate genome-wide methylation profiles of primary chondrocytes from osteoarthritis patients. DESIGN: We compare genome-wide methylation profiles of macroscopically intact (low-grade) and degraded (high-grade) osteoarthritis cartilage samples matched from...

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Share to Epigenetics and DNA Methylation
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PMID: 39053729
DOI: 10.1016/j.joca.2024.07.008

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