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Article

Epigenome-wide methylation haplotype association analysis identified HLA-DRB1, HLA-DRB5 and HLA-DQB1 as risk factors for rheumatoid arthritis.

International journal of immunogenetics - 1 Dec 2023

Xu Jing, Chen Haiyan, Sun Chen, Wei Siyu, Tao Junxian, Jia Zhe, Chen Xingyu, Lv Wenhua, Lv Hongchao, Tang Guoping, Jiang Yongshuai, Zhang Mingming

Abstract excerpt

The aim of this study was to compare nonrandom associations between physically adjacent single methylation polymorphism loci among rheumatoid arthritis (RA) and normal subjects for investigating RA-risk methylation haplotypes (meplotype). With 354 ACPA-positive RA patients and 335 normal controls selected from a case-control study based on Swedish population, we conducted the first RA epigenome-wide meplotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37688529
DOI: 10.1111/iji.12637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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