Article
A meta-analysis identifies driver genes and characterizes the molecular epidemiology of colorectal cancer.
Scientific reports - 17 Feb 2026
Olafsson Sigurgeir, Thorarinsson Thorri, Gudjonsson Sigurjon A, Bustamante Mariana, Gunnarsdottir Helga S, Knutsdottir Hildur, Jonsson Hakon, Magnusson Magnus I, Soebech Emilia, Runarsdottir Hjaltey, Magnusdottir Droplaug N, le Roux Louise, Saemundsdottir Jona, Kristinsdottir Bjarney S, Agnarson Bjarni A, Jonsdottir Erna M, Tryggvason Thordur, Ulfarsson Magnus O, Gudbjartsson Daniel F, Jonasson Jon G, Magnusson Olafur, Stefansson Kari, Rafnar Thorunn
Abstract excerpt
Colorectal cancer is thought to develop through the stepwise accumulation of somatic mutations. Recent years have seen the publications of several studies greatly advancing our understanding of the molecular events driving the disease. However, individual studies tend to be small and additional insights may be obtained through the combination of data from multiple sources. We performed targeted sequencing of 2172...
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