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Article

Aldehyde reductase as potential measurement for retinitis pigmentosa: A two-sample Mendelian randomization (MR) study.

Medicine - 13 Feb 2026

Yan Weiming, Long Pan, Chen Chengming, Zhang Xiaohong, Chen Tao

Abstract excerpt

This study aimed to utilize Mendelian randomization (MR) analysis to investigate potential genetic targets related to aldehyde metabolism in the context of retinitis pigmentosa (RP) and to identify possible therapeutic options. Genome-wide association study data for RP were obtained for MR analysis. We employed various statistical methods, including inverse-variance weighted analysis, to evaluate potential causal...

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Identifiers

PMID: 41686564
DOI: 10.1097/MD.0000000000047637
PMCID: PMC12908768

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