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Article

Allogeneic hematopoietic stem cell transplantation and pre-transplant strategies in patients with NPM1-mutated acute myeloid leukemia: a single center experience.

Scientific reports - 4 Jul 2023

Jäger Paul, Rautenberg Christina, Kaivers Jennifer, Kasprzak Annika, Geyh Stefanie, Baermann Ben-Niklas, Haas Rainer, Germing Ulrich, Schroeder Thomas, Kobbe Guido

Abstract excerpt

Patients with acute myeloid leukemia (AML) and nucleophosmin 1 gene mutations (NPM1mut) show a favorable prognosis with chemotherapy (CT) in the absence of negative prognostic genetic abnormalities. Between 2008 and 2021 64 patients with NPM1mutAML received alloHSCT because of additional adverse prognostic factors (1st line), inadequate response to or relapse during or after CT (2nd line). To expand the evidence...

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Share to Hematopoietic Stem Cell Transplantation
Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm, Residual

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Identifiers

PMID: 37402862
DOI: 10.1038/s41598-023-38037-5
PMCID: PMC10319811

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