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Article

Norovirus Infection in Young Nicaraguan Children Induces Durable and Genotype-Specific Antibody Immunity.

Viruses - 16 Sept 2022

Brewer-Jensen Paul D, Reyes Yaoska, Becker-Dreps Sylvia, González Fredman, Mallory Michael L, Gutiérrez Lester, Zepeda Omar, Centeno Edwing, Vielot Nadja, Diez-Valcarce Marta, Vinjé Jan, Baric Ralph, Lindesmith Lisa C, Bucardo Filemon

Abstract excerpt

There are significant challenges to the development of a pediatric norovirus vaccine, mainly due to the antigenic diversity among strains infecting young children. Characterizing human norovirus serotypes and understanding norovirus immunity in naïve children would provide key information for designing rational vaccine platforms. In this study, 26 Nicaraguan children experiencing their first norovirus acute...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36146859
DOI: 10.3390/v14092053
PMCID: PMC9501366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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