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Article

Serological surveillance of GI norovirus reveals persistence of blockade antibody in a Jidong community-based prospective cohort, 2014-2018.

Frontiers in cellular and infection microbiology - 1 Jan 2023

Yu Jing-Rong, Xie Dong-Jie, Li Jia-Heng, Koroma Mark Momoh, Wang Lu, Wang Yu, Jing Duo-Na, Xu Jia-Yi, Yu Jun-Xuan, Du Hui-Sha, Zhou Fei-Yuan, Liang Zhi-Yan, Zhang Xu-Fu, Dai Ying-Chun

Abstract excerpt

Introduction: Herd immunity against norovirus (NoV) is poorly understood in terms of its serological properties and vaccine designs. The precise neutralizing serological features of genotype I (GI) NoV have not been studied. Methods: To expand insights on vaccine design and herd immunity of NoVs, seroprevalence and seroincidence of NoV genotypes GI.2, GI.3, and GI.9 were determined using blockade antibodies based...

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PMID: 38188632
DOI: 10.3389/fcimb.2023.1258550
PMCID: PMC10766831

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