Article
Estimating genotype-tissue specific gene expression using hybrid deep learning.
Communications biology - 13 May 2026
Dong Jiahong, Brown Stephen, Truong Kevin
Abstract excerpt
Genotype-tissue expression profiles are critical for understanding how genetic variation influences gene regulation across tissues, yet they are often missing or incomplete, and experimental profiling is costly and time-consuming. Although computational approaches exist for multi-tissue imputation and sequence-based expression prediction, they do not explicitly use expression information from neighboring...
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