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Optical Coherence Tomography Abnormalities in NOTCH3 Mutation Carriers: A Matched Case-Control Study From UK Biobank.

The neurologist - 1 May 2026

Vallamchetla Sai Krishna, Badr Amro, Li Xin, Wang Yalin, Meschia James F, Dumitrascu Oana M, Lin Michelle P

Abstract excerpt

OBJECTIVES: This study aims to identify retinal biomarkers of NOTCH3 mutation carriers using optical coherence tomography (OCT) data from the UK Biobank. METHODS: We conducted a cross-sectional, matched case-control study of individuals with or without NOTCH3 mutation from the UK Biobank between 2006 and 2010. All participants had macular OCT scan and cognitive assessment. Cases were identified based on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41662691
DOI: 10.1097/NRL.0000000000000655

Genes

NOTCH3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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