Article

Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypes

2023-05-17

Abstract excerpt

The human retina is a complex multi-layered tissue which offers a unique window into systemic health and disease. Optical coherence tomography (OCT) is widely used in eye care and allows the non-invasive, rapid capture of retinal measurements in exquisite detail. We conducted genome- and phenome-wide analyses of retinal layer thicknesses using macular OCT images from 44,823 UK Biobank participants. We performed ph...

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Literature Corpus work: ef19e305-57f4-5d81-a1d7-21385c08c0ed
DOI: 10.1101/2023.05.16.23290063

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