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Macular thickness varies with age-related macular degeneration genetic risk variants in the UK Biobank cohort

1 Dec 2021

Abstract excerpt

Abstract To evaluate the influence AMD risk genomic variants have on macular thickness in the normal population. UK Biobank participants with no significant ocular history were included using the UK Biobank Resource (project 2112). Spectral-domain optical coherence tomography (SD-OCT) images were taken and segmented to define retinal layers. The influence of AMD risk single-nucleotide polymorphisms (SNP) on...

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PMID: 34853365
DOI: 10.1038/s41598-021-02631-2

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