Article
The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction.
Neuron - 19 May 2005
Francis Michael M, Evans Susan P, Jensen Michael, Madsen David M, Mancuso Joel, Norman Kenneth R, Maricq Andres Villu
Abstract excerpt
Nicotinic (cholinergic) neurotransmission plays a critical role in the vertebrate nervous system, underlies nicotine addiction, and nicotinic receptor dysfunction leads to neurological disorders. The C. elegans neuromuscular junction (NMJ) shares many characteristics with neuronal synapses, including multiple classes of postsynaptic currents. Here, we identify two genes required for the major excitatory current...
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