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Article

Integrative functional genomics analysis identifies pleiotropic genes for vascular diseases.

Nature communications - 5 Feb 2026

Solomon Charles U, McVey David G, Andreadi Catherine, Gong Peng, Turner Lenka, Song Dedrick S S, Zhang Heming, Lee Dominic P, Karamanavi Elisavet, Yang Wei, Chu Jiapeng, Chen Runji, Haworth Kim E, Anene-Nzelu Chukwuemeka George, Li Hui, Denniff Matthew J, Li Peter Y, Zhang Yanhong, Huang Xiaoxin, Morris Gavin E, Greer Peter A, Stringer Emma J, Yu Haojie, Foo Roger S Y, Douglas Gillian, Samani Nilesh J, Webb Tom R, Ye Shu

Abstract excerpt

Several vascular diseases including coronary artery disease, hypertension, stroke, and abdominal aortic aneurysm, have significant genetic underpinnings. Genome-wide association studies have unveiled many genetic loci associated with one or more of these diseases. However, the causative genes at most of these loci are yet to be determined, which hampers the translation of the genetic findings into a better...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41644529
DOI: 10.1038/s41467-026-69273-8
PMCID: PMC13066215

Genes

FES
BCAR1
CARF
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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