Article

Genetic association studies of fibromuscular dysplasia identify new risk loci and shared genetic basis with more common vascular diseases

2020-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Fibromuscular dysplasia (FMD) is an arteriopathy that presents clinically by hypertension and stroke, mostly in early middle-aged women. We report results from the first genome-wide association meta-analysis of FMD including 1962 FMD cases and 7100 controls. We confirmed PHACTR1 and identified three new loci ( LRP1, ATP2B1 , and LIMA1) associated with FMD. Transcriptome-wide association analysis...

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Literature Corpus work: 8a0380f5-3343-5a4d-a152-415f4b7250bb
DOI: 10.1101/2020.09.16.20195701

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