Article
Use of functional genomics to identify candidate genes underlying human genetic association studies of vascular diseases.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2012
Yang Xia
Abstract excerpt
Recent genome-wide association studies have identified hundreds of genetic loci as being associated with vascular diseases or traits and their risk factors. Many of the loci uncovered represent novel discoveries with no obvious candidate genes and molecular mechanisms, testifying to the complexity of vascular diseases. To understand the functional consequences of genetic variations and help pinpoint the...
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