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Article

MAL33 drives natural variation in maltose metabolism in Saccharomyces eubayanus.

Genetics - 4 Apr 2026

Quintrel Pablo, Muñoz-Guzmán Felipe, Villarreal Pablo, Peña Tomas A, Garate Natalia I, Muñoz-Tapia Catalina, Oporto Christian I, Crandall Johnathan G, Larrondo Luis F, Hittinger Chris Todd, Fischer Gilles, Cubillos Francisco A

Abstract excerpt

Maltose is one of the most abundant sugars in brewer's wort, and its efficient utilization is critical for successful fermentation. However, maltose consumption varies naturally among Saccharomyces eubayanus strains isolated from different host trees, such as Quercus and Nothofagus. To identify the genetic determinants underlying these phenotypic differences, we performed bulk segregant analysis and quantitative...

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Identifiers

PMID: 41642680
DOI: 10.1093/genetics/iyag032

Genes

MAL
F2

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