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Article

Virus variant quantification with Orthanq.

BMC bioinformatics - 4 Feb 2026

Uzuner Hamdiye, Wiegand Felix, Schrinner Sven, Lähnemann David, Schadendorf Dirk, Köster Johannes

Abstract excerpt

BACKGROUND: Existing tools for virus variant identification can pinpoint the most abundant virus variant in a sequencing sample. However, patients can be infected by more than one variant of the same virus species or strain, for example by multiple variants of SARS-CoV-2. This leads to the more complicated problem of virus variant quantification from samples containing virus mixtures. RESULTS: We report on...

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PMID: 41639627
DOI: 10.1186/s12859-026-06387-2
PMCID: PMC12930645

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