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Article

Peroxiredoxin 2 contributes to the malignant phenotype of glioblastoma cells.

Biochemical and biophysical research communications - 12 Mar 2026

Szumska Kamila, Sabir Fatmanur, Szeliga Monika

Abstract excerpt

Glioblastoma (GBM) is the most malignant primary brain tumor. To adapt to intrinsic oxidative stress, GBM cells upregulate antioxidant systems. Out of six peroxiredoxins (PRDX) involved in protecting cells from oxidative stress, PRDX1 and PRDX4 are proteins that have been attributed with GBM-promoting properties. The role of PRDX2 in these tumors remains elusive. We have recently reported that treatment with...

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Identifiers

PMID: 41619511
DOI: 10.1016/j.bbrc.2026.153370

Genes

PRDX2
PRDX4
PRDX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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