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Article

Comprehensive analysis of the expression levels and prognostic values of PRDX family genes in glioma.

Neurochemistry international - 1 Feb 2022

Szeliga Monika

Abstract excerpt

Gliomas are a histologically and molecularly heterogeneous group of neoplasms accounting for 80% of malignant primary brain tumors. Growing evidence suggests that production of reactive oxygen species (ROS) is linked to glioma pathogenesis, although it is still unclear whether it is a cause or an effect of this process. Peroxiredoxins (PRDXs), a family of six antioxidant proteins, may promote or inhibit...

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PMID: 34968631
DOI: 10.1016/j.neuint.2021.105256

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