Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Procyanidin B1 Promotes PSMC3‐NRF2 Ubiquitination to Induce Ferroptosis in Glioblastoma

18 Sept 2024

Abstract excerpt

NRF2 signaling is a crucial antioxidant defense mechanism against ferroptosis in tumors, and targeting NRF2 is essential for tumor therapy. However, the effectiveness of NRF2 inhibitors remains unexplored. The active ingredients of traditional Chinese medicine serve as important sources of NRF2 inhibitors. In this study, we established an intracranial glioblastoma (GBM) orthotopic model and observed the effects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39293861
DOI: 10.1002/ptr.8328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Procyanidin B1 Promotes PSMC3‐NRF2 Ubiquitination to Induce Ferroptosis in GlioblastomaPMID 39293861Read ↗

Apatinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 PathwaySemantic proximity Read ↗

Ferroptosis: The Entanglement between Traditional Drugs and Nanodrugs in Tumor TherapySemantic proximity Read ↗

IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2Semantic proximity Read ↗

CXCL8 enhances malignancy of GBM via TNFα-NFκB mediated suppression of ferroptosisSemantic proximity Read ↗

NCOA4 mediated ferritinophagy induced ferroptosis regulates radiosensitivity and prognosis of gliomaSemantic proximity Read ↗

Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer.Semantic proximity Read ↗

Machine learning for the micropeptide encoded by LINC02381 regulates ferroptosis through the glucose transporter SLC2A10 in glioblastomaSemantic proximity Read ↗

Downregulated ferroptosis‐related gene SQLE facilitates temozolomide chemoresistance, and invasion and affects immune regulation in glioblastomaSemantic proximity Read ↗

NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastomaSemantic proximity Read ↗

Ferroptosis assassinates tumor (FAST)Semantic proximity Read ↗

A chiral fluorescent Ir( iii ) complex that targets the GPX4 and ErbB pathways to induce cellular ferroptosisSemantic proximity Read ↗

FTY720 inhibits the Nrf2/ARE pathway in human glioblastoma cell lines and sensitizes glioblastoma cells to temozolomideSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.