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Cell-free DNA in chemical carcinogen induced mouse lung cancer and colon cancer model: its implications in diagnostics and therapeutics.

Molecular genetics and genomics : MGG - 31 Jan 2026

Trivedi Devangkumar D, Shaikh Aafrinbanu M, Patel Saumya K, Dalai Sarat Kumar, Bakshi Sonal R

Abstract excerpt

Chemical carcinogen induced mouse models closely mimic environmentally driven human cancers and provide platforms for studying tumor initiation and progression. However, the behavior and diagnostic value of cell-free DNA (cfDNA) in such models remain poorly understood, limiting their translational utility for biomarker development. Considering the increasing clinical relevance of cfDNA for early detection and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41618999
DOI: 10.1007/s00438-026-02349-8

Genes

AKT1
ALK
APC
BRAF
FGFR1
KRAS
MYC
NF1
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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