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Article

Global burden and genetic insights of RA and JIA in ages 0-19 years: GBD 2021 and MR analysis.

Frontiers in immunology - 1 Jan 2025

An Pingyu, Ma Zhiqiang, Tian Tian, Zhang Shibo, Wang Jian, Tian Zhiliang

Abstract excerpt

Background: Rheumatoid arthritis (RA) is a chronic autoimmune arthritis that predominantly affects adults, whereas juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of childhood-onset arthritides defined by age at onset, clinical phenotype, and immunological profile. Although RA and JIA are classified as distinct diseases, they share overlapping clinical and immunological features, and the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41613114
DOI: 10.3389/fimmu.2025.1661461
PMCID: PMC12847325

Genes

CD28

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