Article
Pathogenesis of rheumatoid arthritis: one year in review 2024.
Clinical and experimental rheumatology - 1 Sept 2024
D'Orazio Andrea, Cirillo Aglaia Lucia, Greco Giulia, Di Ruscio Evy, Latorre Manuela, Pisani Francesco, Alunno Alessia, Puxeddu Ilaria
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterised by joint destruction and extra-articular manifestations. Different cells and soluble components of the innate as well as adaptive immune system actively contribute to the amplification and perpetuation of the inflammatory processes and structural changes. To date, the knowledge on the mechanisms involved in RA pathogenesis is...
Topics
- Humans
- Arthritis, Rheumatoid
- Animals
- Genetic Predisposition to Disease
- Immunity, Innate
- Autoimmunity
- Adaptive Immunity
- Signal Transduction
- Risk Factors
- Inflammation Mediators
