Article
Blood pressure, calcium channel blockers, and the risk of prostate cancer: a Mendelian randomization study.
Cancer causes & control : CCC - 1 Aug 2023
Kazmi Nabila, Valeeva Elena V, Khasanova Gulshat R, Lewis Sarah J, Plotnikov Denis
Abstract excerpt
BACKGROUND: Observational studies have found some evidence of an association between elevated blood pressure and prostate cancer risk; however, the results are inconclusive. We tested whether systolic blood pressure (SBP) influences prostate cancer risk and evaluated the effect of calcium channel blockers (CCB) on the disease using Mendelian randomization (MR) approach. METHODS: We used 278 genetic variants...
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