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Article

Systolic Blood Pressure and Risk of Type 2 Diabetes: A Mendelian Randomization Study.

Diabetes - 1 Feb 2017

Aikens Rachael C, Zhao Wei, Saleheen Danish, Reilly Muredach P, Epstein Stephen E, Tikkanen Emmi, Salomaa Veikko, Voight Benjamin F

Abstract excerpt

Observational studies have shown that elevated systolic blood pressure (SBP) is associated with future onset of type 2 diabetes, but whether this association is causal is not known. We applied the Mendelian randomization framework to evaluate the causal hypothesis that elevated SBP increases risk for type 2 diabetes. We used 28 genetic variants associated with SBP and evaluated their impact on type 2 diabetes...

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Identifiers

PMID: 27702834
DOI: 10.2337/db16-0868
PMCID: PMC5248987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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