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Article

JAK2 V617F, MPL, and CALR mutations in essential thrombocythaemia and major thrombotic complications: a single-institute retrospective analysis.

Pathology oncology research : POR - 1 Jul 2015

Pósfai Éva, Marton Imelda, Király Péter Attila, Kotosz Balázs, Kiss-László Zsuzsanna, Széll Márta, Borbényi Zita

Abstract excerpt

Thrombo-haemorrhagic events are the main cause of morbidity and mortality in essential thrombocythemia. The aim of this study was to estimate the incidence of thrombotic events and the impact of the JAK2V617F, MPL (W515L, W515K, W515R, W515A and S505N) and CALR (type-1, type-2) mutations on 101 essential thrombocythaemia patients (72 females and 29 males with a mean age of 61 years) diagnosed in a Southern...

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Source

Identifiers

PMID: 25573593
DOI: 10.1007/s12253-014-9885-4

Genes

MPL
CALR
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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