Article
One thousand patients with essential thrombocythemia: the Mayo Clinic experience.
Blood cancer journal - 18 Jan 2024
Gangat Naseema, Karrar Omer, Al-Kali Aref, Begna Kebede H, Elliott Michelle A, Wolanskyj-Spinner Alexandra P, Pardanani Animesh, Hanson Curtis A, Ketterling Rhett P, Tefferi Ayalew
Abstract excerpt
We describe 1000 patients with essential thrombocythemia seen at the Mayo Clinic between 1967 and 2023: median age 58 years (18-90), females 63%, JAK2/CALR/MPL-mutated 62%/27%/3%, triple-negative (TN) 8%, extreme thrombocytosis (ExT; platelets ≥1000 × 109/L) 26%, leukocytosis (leukocyte count >11 × 109/L) 20%, and abnormal karyotype 6%. JAK2-mutated patients were older (median 71 years), and CALR mutated (52...
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