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Article

Analysis of CALR-mutated essential thrombocythemia as a distinct disease entity compared with JAK2 V617F-mutated and triple-negative patients.

Turkish journal of medical sciences - 1 Jan 2026

Aydin Gökhan Sami, Aksoy Elif, Yönal Hindilerden İpek, Dağlar Aday Aynur, Gültürk Emine, Nalçaci Meliha, Hindilerden Fehmi

Abstract excerpt

Background/aim: Calreticulin (CALR) mutations in essential thrombocythemia (ET) are associated with younger age, higher platelet counts, and lower thrombosis rates. The present study analyzes the demographic, laboratory, and clinical features of the CALR mutation and its prognostic impact. Materials and methods: The clinical impact of CALR mutations was assessed in 391 ET patients. Results: CALR-mutation patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42058976
DOI: 10.55730/1300-0144.6184
PMCID: PMC13124206

Genes

CALR
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Analysis of CALR-mutated essential thrombocythemia as a distinct disease entity compared with JAK2 V617F-mutated and triple-negative patients.PMID 42058976Read ↗

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