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Article

Contributions of selenoproteins to breast cancer etiology and racial disparity.

Cancer causes & control : CCC - 21 Jan 2026

Bera Soumen, Liu Li, Ma Weiwei, Xu Ziqiao, Sverdlov Maria, Deaton Ryan, Macias Virgilia, Valyi-Nagy Klara, Kajdacsy-Balla Andre, Hoskins Kent, Wiley Elizabeth L, Kastrati Irida, Diamond Alan M

Abstract excerpt

PURPOSE: Breast cancer etiology is multifactorial with African American women experiencing a significant health disparity in clinical presentation and outcomes. The selenium-containing protein SELENOF has been implicated in breast carcinogenesis by cell culture and animal studies. SELENOF translation is highly regulated in part by the RNA helicase eIF4a3, which binds to the key regulatory regions in the SELENOF...

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Source

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Identifiers

PMID: 41563517
DOI: 10.1007/s10552-025-02123-y
PMCID: PMC12823618

Genes

SELENOF
SELENOP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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