Article

Identification of Oncosuppressing Effects of Seven Selenoproteins in Thyroid Cancer: Implications for Distinct Roles of Selenoproteins in Tumorigenesis

2021-04-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Low selenium levels are associated with increased incidence and advanced stage of thyroid cancers. In response to changes in selenium levels, a hierarchy of selenoprotein biosynthesis allows tissue-specific fine-tuning of the 25 selenoproteins. To determine the role of individual selenoproteins on thyroid carcinogenesis, we carried out a multiomic data mining st...

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Literature Corpus work: 2b4e2d0a-176f-58e2-92d2-d6d28a3f8549
DOI: 10.21203/rs.3.rs-402154/v1

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