Article
Correlations of SELENOF and SELENOP genotypes with serum selenium levels and prostate cancer.
The Prostate - 1 Mar 2018
Ekoue Dede N, Ansong Emmanuel, Liu Li, Macias Virgilia, Deaton Ryan, Lacher Craig, Picklo Matthew, Nonn Larisa, Gann Peter H, Kajdacsy-Balla Andre, Prins Gail S, Freeman Vincent L, Diamond Alan M
Abstract excerpt
BACKGROUND: Selenium status is inversely associated with the incidence of prostate cancer. However, supplementation trials have not indicated a benefit of selenium supplementation in reducing cancer risk. Polymorphisms in the gene encoding selenoprotein 15 (SELENOF) are associated with cancer incidence/mortality and present disproportionately in African Americans. Relationships among the genotype of...
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