Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vascular complications in NPM1-Mutated acute myeloid leukemia: clinical features and prognosis.

Annals of hematology - 20 Jan 2026

Wang Xiaoying, Mo Wenbin, Chen Miao, Sui Jingchen, Bian Renjie, Yan Xiaojing

Abstract excerpt

Although nucleophosmin 1 (NPM1) mutation is generally considered a favorable prognostic biomarker in acute myeloid leukemia (AML), its clinical behavior is heterogeneous. A subset of NPM1-mutated patients continues to experience adverse outcomes despite their favorable genotype. We conducted a retrospective analysis of newly diagnosed NPM1-mutated AML patients treated at The First Affiliated Hospital of China...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to fms-Like Tyrosine Kinase 3
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Prognosis

Share to Vascular Diseases

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41557028
DOI: 10.1007/s00277-026-06831-6
PMCID: PMC12819468

Genes

NPM1
FLT3
CD34
EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vascular complications in NPM1-Mutated acute myeloid leukemia: clinical features and prognosis.PMID 41557028Read ↗

[Analysis of risk factors for early death in NPM1-mutated acute myeloid leukemia patients].Semantic proximity Read ↗

Clinical Characteristics, Molecular Analysis and Survival Outcomes of Patients With Extramedullary Acute Myeloid Leukemia: A Retrospective Single-Center Study.Semantic proximity Read ↗

Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations.Semantic proximity Read ↗

Investigations of the prognostic value of RUNX1 mutation in acute myeloid leukemia patients: Data from a real-world study.Semantic proximity Read ↗

Characteristics and clinical behavior of acute myeloid leukemia harboring rare non-A/B/D nucleophosmin (NPM1) gene mutation subtypes: a single-center experience and review of the literature.Semantic proximity Read ↗

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives.Semantic proximity Read ↗

Clinical prognostic value of different NPM1 mutations in acute myeloid leukemia patients.Semantic proximity Read ↗

Cytogenetic abnormalities in NPM1-mutated acute myeloid leukemia.Semantic proximity Read ↗

Biological and clinical consequences of NPM1 mutations in AML.Semantic proximity Read ↗

Clinical outcomes associated with NPM1 mutations in newly diagnosed acute myeloid leukemia.Semantic proximity Read ↗

Acute Myeloid Leukaemia with Normal Cytogenetics and NPM1-Mutation: Impact of Mutation Topography on OutcomesSemantic proximity Read ↗

Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor-risk factor in de novo acute myeloid leukemia patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.