Article
Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations.
Journal of hematology & oncology - 13 May 2022
Eckardt Jan-Niklas, Stölzel Friedrich, Kunadt Desiree, Röllig Christoph, Stasik Sebastian, Wagenführ Lisa, Jöhrens Korinna, Kuithan Friederike, Krämer Alwin, Scholl Sebastian, Hochhaus Andreas, Crysandt Martina, Brümmendorf Tim H, Naumann Ralph, Steffen Björn, Kunzmann Volker, Einsele Hermann, Schaich Markus, Burchert Andreas, Neubauer Andreas, Schäfer-Eckart Kerstin, Schliemann Christoph, Krause Stefan W, Herbst Regina, Hänel Mathias, Hanoun Maher, Kaiser Ulrich, Kaufmann Martin, Rácil Zdenek, Mayer Jiri, Kroschinsky Frank, Berdel Wolfgang E, Ehninger Gerhard, Serve Hubert, Müller-Tidow Carsten, Platzbecker Uwe, Baldus Claudia D, Schetelig Johannes, Bornhäuser Martin, Thiede Christian, Middeke Jan Moritz
Abstract excerpt
BACKGROUND: Extramedullary manifestations (EM) are rare in acute myeloid leukemia (AML) and their impact on clinical outcomes is controversially discussed. METHODS: We retrospectively analyzed a large multi-center cohort of 1583 newly diagnosed AML patients, of whom 225 (14.21%) had EM. RESULTS: AML patients with EM presented with significantly higher counts of white blood cells (p < 0.0001), peripheral blood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.