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Enhanced lymphotoxin alpha DNA hypermethylation and correlation with genetic polymorphism in rheumatoid arthritis among the Chinese population.

Cytokine - 1 Mar 2026

Song Jingjing, Liu Zhen, Xu Xiaohong, Wang Yanni, Yang Fan, Zhang Ting, Zhang Yunqing, Bi Yufei, Pan Zhenglun

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA) is a multifactorial autoimmune disorder characterized by persistent inflammation and joint destruction. Despite advances in understanding RA's immunopathology, its epigenetic regulation remains underexplored, particularly in diverse populations. This study aims to bridge this gap by examining lymphotoxin alpha (LTA) DNA methylation in a Chinese cohort and exploring the...

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Identifiers

PMID: 41548318
DOI: 10.1016/j.cyto.2026.157117

Genes

LTA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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